Additional Use of Trimetazidine in Patients With Chronic Heart Failure
نویسندگان
چکیده
منابع مشابه
Additional use of trimetazidine in patients with chronic heart failure: a meta-analysis.
OBJECTIVES The aim of this meta-analysis was to evaluate the effects of additional trimetazidine (TMZ) treatment on patients with chronic heart failure (CHF). BACKGROUND Conflicting results currently exist on the clinical use of TMZ in CHF patients. METHODS PubMed, MEDLINE, EMBASE, and EBM Reviews databases were searched through November 2010 for randomized controlled trials (RCTs) assessin...
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BACKGROUND Whether additional benefit can be achieved with the use of trimetazidine (TMZ) in patients with chronic heart failure (CHF) remains controversial. We therefore performed a meta-analysis of randomized controlled trials (RCTs) to evaluate the effects of TMZ treatment in CHF patients. METHODS We searched PubMed, EMBASE, and Cochrane databases through October 2013 and included 19 RCTs ...
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The possibility of modifying cardiac metabolism by switching the fuel used by the myocardium could become increasingly important, especially in clinical conditions characterized by reduced energy availability, such as heart failure. Trimetazidine (VastarelMR), an inhibitor of free fatty acid (FFA) oxidation, holds the characteristics to play a fundamental role in the therapeutic strategy of pat...
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The aim of the study was to assess whether trimetazidine (TMZ) could affect dispersion of atrial depolarization and ventricular repolarization. Corrected QT interval (QTc), QTc dispersion (QTc-d), Tpeak-Tend, and Tpeak-Tend dispersion (Tpeak-Tend-d) were measured in 30 patients with chronic heart failure (CHF) before and 6 months after randomization to conventional therapy plus TMZ (17 patients...
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Background: Sleep disorders are common among patients with chronic heart failure (HF), and it can have a significant effect on patients’ daily activities as well as their health. The purpose of this study was to assess sleep quality and its predictors in Iranian patients with chronic HF. Methods : This cross-sectional study was conducted on a sample of 200 patients with HF in two hospitals ...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2012
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2011.11.027